Main Cast
Jared Padalecki as Sam Winchester (22 episodes)
Jensen Ackles as Dean Winchester (22 episodes)
Jim Beaver as Bobby Singer (13 episodes)
Alona Tal as Jo Harvelle (14 episodes)

Recurring Cast
David Tennant as Nathaniel (9 episodes)
Christopher Lambert as Michael (10 episodes)
Viggo Mortensen as Lucifer (7 episodes)
Jared Padalecki as "Samuel Winchester"/the Anti-Christ (5 episodes)


Jared Padalecki as Sam Winchester

Following the events on the military base in Georgia, Sam has several mixed emotions that he's been dealing with over the last four months. On the one hand, he is a normal human for the first time since he was six months old, not a drop of demon blood in his body. On the other hand, any relationship he could have had with Ruby is now a big what if, now that she is dead. This season, Sam will have to sort through these emotions as he helps Dean and Nathaniel avert the apocalypse...

Jensen Ackles as Dean Winchester

You know him, you love him, and if you don't, the fangirls will kill you! Dean Winchester, Champion of God, is up for his biggest task yet this season in averting the apocalypse. With some help from his brother, Bobby, Jo, and Nathaniel, he might be able to scrape something together in time for the end of days...

Jim Beaver as Bobby Singer

Bobby has been having a hell of a time trying to help Sam and Dean fend off the forces of darkness, and now that Lucifer's free, that task is going to become that much harder, and Bobby isn't the young man he used to be...

Alona Tal as Jo Harvelle

The little girl who wanted to grow up to be just like Daddy...Jo Harvelle has lost more in the last few years than ever before. With Ellen's death, Jo has no family left to turn to other than Bobby and the Winchesters. While she's more than happy to help them fight off the demons from Hell, she's determined to avenge her mother's death by killing the Anti-Christ...

David Tennant as Nathaniel

The angel who pulled Dean from Hell after Lilith sent him there, Nathaniel has gone from Angelic Rebel to the Company's Golden Boy, back to rebel against Heaven. Though likely the most likeable of the angels, he is still quite foreign sometimes to Sam and Dean and lets nothing distract him from their goal of stopping Lucifer and the Anti-Christ...

Christopher Lambert as Michael

The most powerful of all of God's angels, Michael has been hiding from his brothers for reasons unknown, though he did come to save Nathaniel from death by Seraphina.

Viggo Mortensen as Lucifer

Having been locked up in Hell for quite a while, Lucifer is not a happy camper. Nevertheless, he's holding nothing against any of his dear brothers...really...

Jared Padalecki as "Samuel Winchester"/The Anti-Christ

Sam Winchester went to Stanford and got his law degree, assisting in the election of President James Burns and subsequently becoming one of the youngest State Representatives ever elected. However, something sinister is behind Washington's new Golden Boy...something very, very infernal...